Know more

Our use of cookies

Cookies are a set of data stored on a user’s device when the user browses a web site. The data is in a file containing an ID number, the name of the server which deposited it and, in some cases, an expiry date. We use cookies to record information about your visit, language of preference, and other parameters on the site in order to optimise your next visit and make the site even more useful to you.

To improve your experience, we use cookies to store certain browsing information and provide secure navigation, and to collect statistics with a view to improve the site’s features. For a complete list of the cookies we use, download “Ghostery”, a free plug-in for browsers which can detect, and, in some cases, block cookies.

Ghostery is available here for free:

You can also visit the CNIL web site for instructions on how to configure your browser to manage cookie storage on your device.

In the case of third-party advertising cookies, you can also visit the following site:, offered by digital advertising professionals within the European Digital Advertising Alliance (EDAA). From the site, you can deny or accept the cookies used by advertising professionals who are members.

It is also possible to block certain third-party cookies directly via publishers:

Cookie type

Means of blocking

Analytical and performance cookies

Google Analytics

Targeted advertising cookies


The following types of cookies may be used on our websites:

Mandatory cookies

Functional cookies

Social media and advertising cookies

These cookies are needed to ensure the proper functioning of the site and cannot be disabled. They help ensure a secure connection and the basic availability of our website.

These cookies allow us to analyse site use in order to measure and optimise performance. They allow us to store your sign-in information and display the different components of our website in a more coherent way.

These cookies are used by advertising agencies such as Google and by social media sites such as LinkedIn and Facebook. Among other things, they allow pages to be shared on social media, the posting of comments, and the publication (on our site or elsewhere) of ads that reflect your centres of interest.

Our EZPublish content management system (CMS) uses CAS and PHP session cookies and the New Relic cookie for monitoring purposes (IP, response times).

These cookies are deleted at the end of the browsing session (when you log off or close your browser window)

Our EZPublish content management system (CMS) uses the XiTi cookie to measure traffic. Our service provider is AT Internet. This company stores data (IPs, date and time of access, length of the visit and pages viewed) for six months.

Our EZPublish content management system (CMS) does not use this type of cookie.

For more information about the cookies we use, contact INRA’s Data Protection Officer by email at or by post at:

24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

Menu Logo Principal AgroBRC RARe - Agronomic Resources for Research

Home page

Microbiotherapy: towards standardization of fecal microbiota transplants

INRAE / La salle de biobanking robotisée de SAMBO avec une capacité de 600000 échantillons de feces et d’ADN de microbiotes ».
With the first successful Phase III trials for the treatment of Clostridioides difficile infections, it is reasonable to expect that the number of indications for microbiotherapy (fecal microbiota transplantation) will increase considerably, requiring at the same time standardized procedures for using stabilized grafts.

In an article published in Scientific Reports, researchers from MetaGenoPolis and Micalis (INRAE, UPSaclay, Jouy-en-Josas), propose a comparative evaluation of the performance of two new cryoprotectants (a product that protects living cells from very low temperatures) for frozen human fecal transplants in germ-free mice.
High resolution shotgun metagenomic sequencing was used to evaluate the effect of these new cryoprotectants and storage time on graft kinetics and efficiency. The main results show that these cryoprotectants allow to obtain taxonomic profiles closest to the reference. In particular, they favor the survival and implantation of bacterial species important for health, as well as the non-proliferation of undesirable species. The results also draw attention to the need to continue efforts to further improve the survival of very sensitive species belonging to the Lachnospiraceae and Ruminoccocaceae families, whose full survival is to be sought to ensure the full success of a fecal transplant.
The SAMBO platform of MGP, a BRC of the microbial pillar of RARe, is involved in this study for the conservation and automatic extraction of DNA from fecal samples or preparations inoculated to animals.

  • Contact : magali.berland(at)

See also


Berland, M., Cadiou, J., Levenez, F. et al. High engraftment capacity of frozen ready-to-use human fecal microbiota transplants assessed in germ-free mice. Sci Rep 11, 4365 (2021).